Shane Mosley scored his second-straight knockout win of the year, finishing Venezuelan Olympian Patrick Lopez at 2:00 of the 10th and final round at Arena Roberto Duran in Panama City, Panama.

Mosley, 44, who said on his Twitter account that he took the fight on just three weeks’ notice, had to overcome an accidental headbutt which cut him between the eyes less than two minutes into the fight.

Though he was fighting with blood streaming down intermittently, Mosley (49-9-1, 41 knockouts) was able to find the target on the southpaw, flooring Lopez with a leaping left hook near the end of Round 2 that left the 37-year-old wobbly legged but able to survive the round.

Lopez (23-6, 14 KOs) proved durable, having previously been stopped just once in his career (by Tim Coleman in three rounds in 2010). Still, he was unable to put enough punishment on Mosley to dissuade the former three-division world champion, missing with left hands that left him open for Mosley’s sweeping power shots.

Mosley was thoroughly ahead in Round 10 when another left hook sent Lopez skidding to the canvas less than a minute in. Lopez rose but caught a right hand and fell into Mosley, but it wasn’t ruled a knockdown. A left hook that put Lopez back down was ruled one though, and a follow-up bevy of punches ended the fight for good.

Mosley, who is approaching his 23rd year as a pro boxer, is a lock for the Hall of Fame when he finally retires and stays retired, but his post-fight talk on Twitter didn’t seem to hint at this being his farewell fight in Latin America.

“I worked hard the weeks I had b4 the fight & I looked damn good. U haters let me enjoy my hard work & win just 1 day,” tweeted the Pomona, California, resident.

In the main event, No. 10-rated junior bantamweight Luis Concepcion earned revenge against Hernan Marquez, shutting out the former flyweight titleholder from Mexico over 12 rounds to win by the scores 120-107, 120-107 and 120-109. Concepcion scored the fight’s only knockdown in Round 5.

The Panamanian Concepcion (34-4, 24 KOs) retained the “interim” WBA junior bantamweight title, which THE RING doesn’t recognize as a legitimate world championship.

Concepcion, 30, had held the belt (which Marquez (39-7-1, 28 KOs) was not eligible to win as he weighed in nearly two pounds over the limit) several times, but fell short in three shots at legitimate belts, including twice against Marquez, having been knocked out in 11 rounds in their first match and one round in the rematch, both of which took place in 2011 and were for the WBA flyweight title.

A third title shot at the WBC junior bantamweight title this past April ended in Concepcion losing a decision to Carlos Cuadras in Mexico.