Antonio Margarito was denied a professional boxing license by the California State Athletic Commission on Wednesday.

The commission voted 5-1 to reject the former welterweight titleholder's application to reinstate the license that was revoked last year after he and his former trainer, Javier Capetillo, were found guilty of attempting to illegally load his handwraps before a bout against Shane Mosley in January of last year.

Margarito, who fought in Mexico in May and applied for a Nevada license last month, was allowed to apply for a new license in California after a period of one year.

California's ruling could complicate where Margarito's next scheduled fight — a Nov. 13 showdown against Manny Pacquiao — takes place. The Tijuana native's promoter, Bob Arum of Top Rank Inc., had hoped to stage the pay-per-view event at Cowboys Stadium in Arlington, Texas, where Pacquiao was able to draw 50,000 against Joshua Clottey in March.

Margarito will now have to apply for a Texas license without the blessing of the California commission. State commissions usually uphold the decisions of other commissions, especially in regard to suspended or revoked licenses.

However, commissions do occasionally rule against the decisions of other U.S. jurisdictions. The Texas commission licensed now-deceased former junior lightweight titleholder Edwin Valero in 2008, overruling a medical suspension imposed by the New York commission.

The Tennessee commission licensed Mike Tyson in 2002 after the former heavyweight champ had been suspended in Nevada, New York and New Jersey. Tyson challenged heavyweight champ Lennox Lewis in Memphis in 2002.